CTX+Test

CTX: In [|bone physiology], ** the C-terminal telopeptide ** (or more formally, ** carboxy-terminal collagen crosslinks ** , and known by the [|acronym] ** CTX ** ) is a [|serum] [|biomarker] used to measure the rate of [|bone turnover]. It can be useful in assisting clinicians to determine a patient's nonsurgical treatment response as well as evaluate a patient's risk of developing complications during healing following surgical intervention. [|[1]] The test used to detect the CTX marker is called the Serum CrossLaps, and it is more specific to bone resorption than any other test currently available

The CTX test measures for the presence and concentration of a crosslink [|peptide] sequence of [|type I collagen], found, among other tissues, in bone. This specific peptide sequence relates to bone turnover because it is the portion that is cleaved by [|osteoclasts] during bone resorption, and its serum levels are therefore proportional to osteoclastic activity at the time the blood sample is drawn. [|[1]] Serum levels in healthy patients not taking bisphosphonates tends to **hover above 300** ** [|pg] /mL. **